In practice, the main differences between developing for developing for the Nicman Vault service and developing for Amazon S3 are:
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As detailed in this document, the Vault service supports the great majority of but not the entire Amazon S3 API.
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Also as detailed in this document, the Vault service supports a small number of extensions to the Amazon S3 API.
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Vault client applications must use the Nicman Vault service endpoint rather than the Amazon S3 service endpoint.
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You will need to use either the Vault Management Console or the Nicman Vault Administration API to create and manage service user accounts.